Maternal Gene Polymorphisms Involved in Folate Metabolism as Risk Factors for Down Syndrome Offspring in Southern Brazil

This study aimed to investigate the role of maternal polymorphisms, as well as their risk genotypes combinations of MTR A2756G, MTRR A66G, CBS 844ins68, and RFC A80G, involved in folate/homocysteine metabolism, as possible risk factors for Down syndrome (DS) in Southern Brazil. A case-control study...

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Main Authors: Brandalize, Ana Paula Carneiro, Bandinelli, Eliane, Santos, Pollyanna Almeida Dos, Schüler-Faccini, Lavínia
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835528/
https://ncbi.nlm.nih.gov/pubmed/21045269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2010-0731
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