Maternal Risk for Down Syndrome Is Modulated by Genes Involved in Folate Metabolism

Studies have shown that the maternal risk for Down syndrome (DS) may be modulated by alterations in folate metabolism. The aim of this study was to evaluate the influence of 12 genetic polymorphisms involved in folate metabolism on maternal risk for DS. In addition, we evaluated the impact of these...

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Autori principali: Zampieri, Bruna Lancia, Biselli, Joice Matos, Goloni-Bertollo, Eny Maria, Vannucchi, Hélio, Carvalho, Valdemir Melechco, Cordeiro, José Antônio, Pavarino, Érika Cristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826801/
https://ncbi.nlm.nih.gov/pubmed/22377700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2011-0869
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