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A New Method for Quantitative Immunoblotting of Endogenous α-Synuclein

β-Sheet-rich aggregates of α-synuclein (αSyn) are the hallmark neuropathology of Parkinson’s disease and related synucleinopathies, whereas the principal native structure of αSyn in healthy cells - unfolded monomer or α-helically folded oligomer - is under debate. Our recent crosslinking analysis of...

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Détails bibliographiques
Auteurs principaux: Newman, Andrew J., Selkoe, Dennis, Dettmer, Ulf
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835431/
https://ncbi.nlm.nih.gov/pubmed/24278419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081314
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