Regulation of Skeletal Muscle Oxidative Capacity and Insulin Signaling by the Mitochondrial Rhomboid Protease PARL

Type 2 diabetes Mellitus (T2DM) and aging are characterized by insulin resistance, lower mitochondrial density and function and increased production of reactive oxygen species (ROS). In lower organisms continuous remodeling critically maintains the function and life cycle of mitochondria, in part by...

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Autors principals: Civitarese, Anthony E., MacLean, Paul S., Carling, Stacy, Kerr-Bayles, Lyndal, McMillan, Ryan P., Pierce, Anson, Becker, Thomas C., Moro, Cedric, Finlayson, Jean, Lefort, Natalie, Newgard, Christopher B., Mandarino, Lawrence, Cefalu, William, Walder, Ken, Collier, Greg R., Hulver, Matthew W., Smith, Steven R., Ravussin, Eric
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835349/
https://ncbi.nlm.nih.gov/pubmed/20444421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.04.004
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