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Stromal Cell-Independent B-Cell Development In Vitro: Generation and Recovery of Autoreactive Clones
We describe and characterize a stromal-cell independent culture system that efficiently supports pro-B cell to IgM(+) B-cell development with near normal levels of IgH and Igκ diversity. Pro-B cells present in non-adherent bone marrow cells proliferate in the presence of IL-7 and subsequent to the r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835306/ https://ncbi.nlm.nih.gov/pubmed/20109461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2010.01.007 |
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