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An Endogenously Produced Fragment of Cardiac Myosin Binding Protein C is Pathogenic and Can Lead to Heart Failure
RATIONALE: A stable 40 kD fragment is produced from cardiac myosin binding protein-C (cMyBP-C) when the heart is stressed, using a stimulus such as ischemia reperfusion injury. Elevated levels of the fragment can be detected in both the diseased mouse and human heart but its ability to interfere wit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835189/ https://ncbi.nlm.nih.gov/pubmed/23852539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301225 |
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