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Comparative Metabolomic Analysis of An Alternative Biosynthetic Pathway to Pseudosugars in Actinosynnema mirum DSM 43827

Through a combination of genome mining, gene knockouts, and comparative metabolomic studies, a new biosynthetic pathway to validoxylamine A has been discovered in Actinosynnema mirum DSM 43827. The study revealed the rich diversity of biosynthetic pathways to pseudosugar-containing natural products.

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Detalhes bibliográficos
Main Authors: Asamizu, Shumpei, Abugreen, Mostafa, Mahmud, Taifo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835175/
https://ncbi.nlm.nih.gov/pubmed/23939727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300384
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