The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum

Maytansinoids are potent antitumor agents found in plants and microorganisms. To elucidate their biosynthesis at the biochemical and genetic level and to set the stage for their structure modification through genetic engineering, we have cloned two gene clusters required for the biosynthesis of the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Yu, Tin-Wein, Bai, Linquan, Clade, Dorothee, Hoffmann, Dietmar, Toelzer, Sabine, Trinh, Khue Q., Xu, Jun, Moss, Steven J., Leistner, Eckhard, Floss, Heinz G.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123004/
https://ncbi.nlm.nih.gov/pubmed/12060743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092697199
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker