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Development of an economical fermentation platform for enhanced ansamitocin P-3 production in Actinosynnema pretiosum
Abstract Background Ansamitocin P-3 (AP-3), produced by Actinosynnema pretiosum, has extraordinary antitumor activity and has been used as toxic “warhead” in antibody-conjugated drugs. However, AP-3 production is limited by its low yield and thus the high cost of fermentation. In this study, we aime...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SpringerOpen
2019-01-01
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| Colecção: | Bioresources and Bioprocessing |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s40643-018-0235-3 |
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