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Evolutionary Divergence of Sedoheptulose 7-phosphate Cyclases Leads to Several Distinct Cyclic Products

Sedoheptulose 7-phosphate cyclases are enzymes that utilize the pentose phosphate pathway intermediate, sedoheptulose 7-phosphate, to generate cyclic precursors of many bioactive natural products, such as the antidiabetic drug acarbose, the crop protectant validamycin, and the natural sunscreens myc...

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Detalhes bibliográficos
Main Authors: Asamizu, Shumpei, Xie, Pengfei, Brumsted, Corey J., Flatt, Patricia M., Mahmud, Taifo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405187/
https://ncbi.nlm.nih.gov/pubmed/22741921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3041866
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