Dithiolethione modified valproate and diclofenac increase E-cadherin expression and decrease proliferation of non-small cell lung cancer cells

The effects of dithiolethione-modified valproate, diclofenac and sulindac on non-small cell lung cancer (NSCLC) cells were investigated. Sulfur(S)-valproate and S-diclofenac at 1 μg/ml concentrations significantly reduced prostaglandin (PG)E(2) levels in NSCLC cell lines A549 and NCI-H1299 as did th...

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Main Authors: Moody, Terry W., Switzer, Christopher, Santana-Flores, Wilmarie, Ridnour, Lisa A., Berna, Marc, Thill, Michelle, Jensen, Robert T., Sparatore, Anna, Del Soldato, Piero, Yeh, Grace C, Roberts, David D., Giaccone, Giuseppe, Wink, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835159/
https://ncbi.nlm.nih.gov/pubmed/19628293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2009.06.012
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