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Dithiolethione Compounds Inhibit Akt Signaling in Human Breast and Lung Cancer Cells by Increasing PP2A Activity
The chemo-preventative effects of dithiolethione compounds are attributed to their activation of anti-oxidant response elements (ARE) by reacting with the Nrf2/Keap1 protein complex. In this study, we demonstrate anti-proliferative effects of the dithiolethione compound ACS-1 in human cancer cell li...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472634/ https://ncbi.nlm.nih.gov/pubmed/19701246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.244 |
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