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Modulation of Carcinogen Activation and Detoxification by Novel Dithiolethione-Modified NSAIDs in Human Hepatoma HepG2 and Colon LS180 Cells
PURPOSE: Nonsteroidal anti-inflammatory drugs (NSAIDs) are promising chemopreventive agents against colon and other cancers. However the molecular basis mediated by NSAIDs for chemoprevention has not been fully elucidated. Environmental carcinogens induce DNA mutation and cellular transformation; th...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755634/ https://ncbi.nlm.nih.gov/pubmed/19276279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1870 |
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