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Targeting SET/I(2)PP2A Oncoprotein Functions as a Multi-pathway Strategy for Cancer Therapy
The SET oncoprotein participates in cancer progression by affecting multiple cellular processes, inhibiting the tumor suppressor PP2A and inhibiting the metastasis suppressor nm23-H1. Based upon these multiple activities, we hypothesized that targeted inhibition of SET would have multiple discrete a...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107340/ https://ncbi.nlm.nih.gov/pubmed/21297667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.622 |
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