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Structural basis for Z-DNA binding and stabilization by the zebrafish Z-DNA dependent protein kinase PKZ

The RNA-dependent protein kinase PKR plays a central role in the antiviral defense of vertebrates by shutting down protein translation upon detection of viral dsRNA in the cytoplasm. In some teleost fish, PKZ, a homolog of PKR, performs the same function, but surprisingly, instead of dsRNA binding d...

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Bibliografski detalji
Glavni autori: de Rosa, Matteo, Zacarias, Sonia, Athanasiadis, Alekos
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834819/
https://ncbi.nlm.nih.gov/pubmed/23975196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt743
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