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The Structure of the Cyprinid herpesvirus 3 ORF112-Zα·Z-DNA Complex Reveals a Mechanism of Nucleic Acids Recognition Conserved with E3L, a Poxvirus Inhibitor of Interferon Response

In vertebrate species, the innate immune system down-regulates protein translation in response to viral infection through the action of the double-stranded RNA (dsRNA)-activated protein kinase (PKR). In some teleost species another protein kinase, Z-DNA-dependent protein kinase (PKZ), plays a simila...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kuś, Krzysztof, Rakus, Krzysztof, Boutier, Maxime, Tsigkri, Theokliti, Gabriel, Luisa, Vanderplasschen, Alain, Athanasiadis, Alekos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692202/
https://ncbi.nlm.nih.gov/pubmed/26559969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.679407
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