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Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts

During S phase, the entire genome must be precisely duplicated, with no sections of DNA left unreplicated. Here, we develop a simple mathematical model to describe the probability of replication failing due to the irreversible stalling of replication forks. We show that the probability of complete g...

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Bibliografische gegevens
Hoofdauteurs: Newman, Timothy J., Mamun, Mohammed A., Nieduszynski, Conrad A., Blow, J. Julian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834809/
https://ncbi.nlm.nih.gov/pubmed/23963700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt728
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