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Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts
During S phase, the entire genome must be precisely duplicated, with no sections of DNA left unreplicated. Here, we develop a simple mathematical model to describe the probability of replication failing due to the irreversible stalling of replication forks. We show that the probability of complete g...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834809/ https://ncbi.nlm.nih.gov/pubmed/23963700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt728 |
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