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The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development
Oxidation of retinol via retinaldehyde results in the formation of the essential morphogen all-trans-retinoic acid (ATRA). Previous studies have identified critical roles in the regulation of embryonic ATRA levels for retinol, retinaldehyde, and ATRA-oxidizing enzymes; however, the contribution of r...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834788/ https://ncbi.nlm.nih.gov/pubmed/24005908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-227967 |
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