Aging enhances release of exosomal cytokine mRNAs by Aβ(1-42)-stimulated macrophages

Amyloid-β(1-42) (Aβ) peptide effects on human models of central nervous system (CNS)-patrolling macrophages (Ms) and CD4 memory T-cells (CD4-Tms) were investigated to examine immune responses to Aβ in Alzheimer's disease. Aβ and lipopolysaccharide (LPS) elicited similar M cytokine and exosomal...

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Autors principals: Mitsuhashi, Masato, Taub, Dennis D., Kapogiannis, Dimitrios, Eitan, Erez, Zukley, Linda, Mattson, Mark P., Ferrucci, Luigi, Schwartz, Janice B., Goetzl, Edward J.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2013
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834783/
https://ncbi.nlm.nih.gov/pubmed/24014820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-238980
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