SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium

BACKGROUND AND PURPOSES: Myocardial C-type natriuretic peptide (CNP) levels are increased in heart failure. CNP can induce negative inotropic (NIR) and positive lusitropic responses (LR) in normal hearts, but its effects in failing hearts are not known. We studied the mechanism of CNP-induced NIR an...

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Dettagli Bibliografici
Autori principali: Moltzau, L R, Aronsen, J M, Meier, S, Nguyen, C H T, Hougen, K, Ørstavik, Ø, Sjaastad, I, Christensen, G, Skomedal, T, Osnes, J-B, Levy, F O, Qvigstad, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834760/
https://ncbi.nlm.nih.gov/pubmed/23808942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12282
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