SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium

BACKGROUND AND PURPOSES: Myocardial C-type natriuretic peptide (CNP) levels are increased in heart failure. CNP can induce negative inotropic (NIR) and positive lusitropic responses (LR) in normal hearts, but its effects in failing hearts are not known. We studied the mechanism of CNP-induced NIR an...

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Bibliografiske detaljer
Main Authors: Moltzau, L R, Aronsen, J M, Meier, S, Nguyen, C H T, Hougen, K, Ørstavik, Ø, Sjaastad, I, Christensen, G, Skomedal, T, Osnes, J-B, Levy, F O, Qvigstad, E
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2013
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834760/
https://ncbi.nlm.nih.gov/pubmed/23808942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12282
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