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High salt-induced hypertension in B(2) knockout mice is corrected by the ET(A) antagonist, A127722

BACKGROUND AND PURPOSE: The contribution of endothelin-1 (ET-1) in a B(2)KO mouse model of a high salt-induced arterial hypertension was investigated. EXPERIMENTAL APPROACH: Wild-type (WT) or B(2)KO mice receiving a normal diet (ND) or a high-salt diet (HSD) were monitored by radiotelemetry up to a...

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Detalhes bibliográficos
Main Authors: Brochu, I, Houde, M, Desbiens, L, Simard, E, Gobeil, F, Semaan, W, Bkaily, G, D'Orléans-Juste, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834752/
https://ncbi.nlm.nih.gov/pubmed/23713522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12259
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