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Combined effects of AT(1) and ET(A) receptor antagonists, candesartan, and A-127722 in DOCA–salt hypertensive rats

Several recent studies have provided evidence that many of the hemodynamic and mitogenic actions of angiotensin II (Ang II) are mediated by endothelin-1 (ET-1). We hypothesized that Ang II and ET-1 act synergistically to promote a decline in renal function and the development of renal fibrosis in th...

詳細記述

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書誌詳細
主要な著者: Pollock, David M., Derebail, Vimal K., Yamamoto, Tatsuo, Pollock, Jennifer S.
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939804/
https://ncbi.nlm.nih.gov/pubmed/11368889
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