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Pressor and pulmonary responses to ET-1(1–31) in guinea-pigs
1. Endothelin-1(1–31) (ET-1(1–31); 0.25 to 4 nmol kg(−1); i.v.) induced, in the guinea-pig, graded increases in MAP and an indomethacin-sensitive enhancement of pulmonary insufflation pressure (PIP). At all doses, ET-1(1–31) induced a monophasic pressor response, except at 4 nmol kg(−1), which cause...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573412/ https://ncbi.nlm.nih.gov/pubmed/12110606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704782 |
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