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Pressor and pulmonary responses to ET-1(1–31) in guinea-pigs

1. Endothelin-1(1–31) (ET-1(1–31); 0.25 to 4 nmol kg(−1); i.v.) induced, in the guinea-pig, graded increases in MAP and an indomethacin-sensitive enhancement of pulmonary insufflation pressure (PIP). At all doses, ET-1(1–31) induced a monophasic pressor response, except at 4 nmol kg(−1), which cause...

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Detaylı Bibliyografya
Asıl Yazarlar: Honoré, Jean-Claude, Plante, Mirco, Bkaily, Ghassan, Rae, Giles A, D'Orléans-Juste, Pedro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573412/
https://ncbi.nlm.nih.gov/pubmed/12110606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704782
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