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Nitric oxide limits the eicosanoid-dependent bronchoconstriction and hypotension induced by endothelin-1 in the guinea-pig

1. This study attempts to investigate if endogenous nitric oxide (NO) can modulate the eicosanoid-releasing properties of intravenously administered endothelin-1 (ET-1) in the pulmonary and circulatory systems in the guinea-pig. 2. The nitric oxide synthase blocker N(ω)-nitro-L-arginine methyl ester...

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Detalhes bibliográficos
Main Authors: Lewis, Karina, Cadieux, Alain, Rae, Giles A, Gratton, Jean-Philippe, D'Orléans-Juste, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565784/
https://ncbi.nlm.nih.gov/pubmed/10051125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702274
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