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PK/PD models in antibacterial development
There is an urgent need for novel antibiotics to treat life-threatening infections caused by bacterial ‘superbugs’. Validated in vitro pharmacokinetic/pharmacodynamic (PK/PD) and animal infection models have been employed to identify the most predictive PK/PD indices and serve as key tools in the an...
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| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834155/ https://ncbi.nlm.nih.gov/pubmed/23871724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2013.06.010 |
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