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Hepatocyte Nuclear Factors 4α and 1α Regulate Kidney Developmental Expression of Drug-Metabolizing Enzymes and Drug Transporters
The transcriptional regulation of drug-metabolizing enzymes and transporters (here collectively referred to as DMEs) in the developing proximal tubule (PT) is not well understood. As in the liver, DME regulation in the PT may be mediated through nuclear receptors, which are thought to “sense” deviat...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834141/ https://ncbi.nlm.nih.gov/pubmed/24038112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.088229 |
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