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Hypoxia reduces CD138 expression and induces an immature and stem cell-like transcriptional program in myeloma cells

Although CD138 expression is a hallmark of plasma cells and myeloma cells, reduced CD138 expression is occasionally found. However, the mechanisms underlying CD138 downregulation in myeloma cells remain unclear. Previous reports suggest that the bone marrow microenvironment may contribute to CD138 d...

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Detalhes bibliográficos
Main Authors: KAWANO, YAWARA, KIKUKAWA, YOSHITAKA, FUJIWARA, SHIHO, WADA, NAOKO, OKUNO, YUTAKA, MITSUYA, HIROAKI, HATA, HIROYUKI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834117/
https://ncbi.nlm.nih.gov/pubmed/24126540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.2134
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