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PDK1 inhibition is a novel therapeutic target in multiple myeloma
BACKGROUND: Cancer cells utilise the glycolytic pathway even when adequate oxygen is present, a phenomenon known as the Warburg effect. We examined whether this system is operative in multiple myeloma (MM) cells and whether glycolysis inhibition is a potential therapeutic modality. METHODS: The MM c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553526/ https://ncbi.nlm.nih.gov/pubmed/23321518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.527 |
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