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Short Telomeres: From Dyskeratosis Congenita to Sporadic Aplastic Anemia and Malignancy

Telomeres are DNA-protein structures that form a protective cap on chromosome ends. As such, they prevent the natural ends of linear chromosomes from being subjected to DNA repair activities that would result in telomere fusion, degradation or recombination. Both the DNA and protein components of th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gramatges, Maria M., Bertuch, Alison A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834083/
https://ncbi.nlm.nih.gov/pubmed/23732052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2013.05.003
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