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Short Telomeres: From Dyskeratosis Congenita to Sporadic Aplastic Anemia and Malignancy

Telomeres are DNA-protein structures that form a protective cap on chromosome ends. As such, they prevent the natural ends of linear chromosomes from being subjected to DNA repair activities that would result in telomere fusion, degradation or recombination. Both the DNA and protein components of th...

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Detalhes bibliográficos
Main Authors: Gramatges, Maria M., Bertuch, Alison A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834083/
https://ncbi.nlm.nih.gov/pubmed/23732052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2013.05.003
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