טוען...
Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant
Arrestin-1 binds light-activated phosphorhodopsin and ensures timely signal shutoff. We show that high transgenic expression of an arrestin-1 mutant with enhanced rhodopsin binding and impaired oligomerization causes apoptotic rod death in mice. Dark rearing does not prevent mutant-induced cell deat...
שמור ב:
| Main Authors: | , , , , , , , , , , , , , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3833262/ https://ncbi.nlm.nih.gov/pubmed/24012956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.08.022 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|