Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value

BACKGROUND: The DNA-repair gene DNA-dependent kinase catalytic subunit (DNA-PKcs) favours or inhibits carcinogenesis, depending on the cancer type. Its role in human hepatocellular carcinoma (HCC) is unknown. METHODS: DNA-dependent protein kinase catalytic subuni, H2A histone family member X (H2AFX)...

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Bibliografische gegevens
Hoofdauteurs: Evert, M, Frau, M, Tomasi, M L, Latte, G, Simile, M M, Seddaiu, M A, Zimmermann, A, Ladu, S, Staniscia, T, Brozzetti, S, Solinas, G, Dombrowski, F, Feo, F, Pascale, R M, Calvisi, D F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
Onderwerpen:
Molecular Diagnostics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833205/
https://ncbi.nlm.nih.gov/pubmed/24136149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.606
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