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Deregulation of methionine metabolism as determinant of progression and prognosis of hepatocellular carcinoma
The under-regulation of liver-specific MAT1A gene codifying for S-adenosylmethionine (SAM) synthesizing isozymes MATI/III, and the up-regulation of widely expressed MAT2A, MATII isozyme occurs in hepatocellular carcinoma (HCC). MATα1:MATα2 switch strongly contributes to the fall in SAM liver content...
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| Publicado en: | Transl Gastroenterol Hepatol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
AME Publishing Company
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044036/ https://ncbi.nlm.nih.gov/pubmed/30050996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tgh.2018.06.04 |
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