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Annular PIP(3) accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse
The immunological synapse formed by a T lymphocyte on the surface of a target cell contains a peripheral ring of filamentous actin (F-actin) that promotes adhesion and facilitates the directional secretion of cytokines and cytolytic factors. We show that growth and maintenance of this F-actin ring i...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832928/ https://ncbi.nlm.nih.gov/pubmed/24190432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131324 |
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