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Interaction between c-jun and Androgen Receptor Determines the Outcome of Taxane Therapy in Castration Resistant Prostate Cancer

Taxane based chemotherapy is the standard of care treatment in castration resistant prostate cancer (CRPC). There is convincing evidence that taxane therapy affects androgen receptor (AR) but the exact mechanisms have to be further elucidated. Our studies identified c-jun as a crucial key player whi...

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Main Authors: Tinzl, Martina, Chen, Binshen, Chen, Shao-Yong, Semenas, Julius, Abrahamsson, Per-Anders, Dizeyi, Nishtman
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832643/
https://ncbi.nlm.nih.gov/pubmed/24260253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079573
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