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Interaction between c-jun and Androgen Receptor Determines the Outcome of Taxane Therapy in Castration Resistant Prostate Cancer

Taxane based chemotherapy is the standard of care treatment in castration resistant prostate cancer (CRPC). There is convincing evidence that taxane therapy affects androgen receptor (AR) but the exact mechanisms have to be further elucidated. Our studies identified c-jun as a crucial key player whi...

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Detalhes bibliográficos
Main Authors: Tinzl, Martina, Chen, Binshen, Chen, Shao-Yong, Semenas, Julius, Abrahamsson, Per-Anders, Dizeyi, Nishtman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832643/
https://ncbi.nlm.nih.gov/pubmed/24260253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079573
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