White Matter Integrity and Executive Abilities Following Treatment with Tetrahydrobiopterin (BH(4)) in Individuals with Phenylketonuria

Tetrahydrobiopterin (BH(4)) lowers blood phenylalanine (Phe) in individuals with PKU who are responders, but its effects on the brain and cognition have not been explored thoroughly. We examined blood Phe, microstructural white matter integrity, and executive abilities in 12 BH(4) responders before...

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Main Authors: White, Desirée A., Antenor-Dorsey, Jo Ann V., Grange, Dorothy K., Hershey, Tamara, Rutlin, Jerrel, Shimony, Joshua S., McKinstry, Robert C., Christ, Shawn E.
格式: Artigo
語言:Inglês
出版: 2013
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832288/
https://ncbi.nlm.nih.gov/pubmed/23928118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2013.07.010
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