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The effects of tetrahydrobiopterin (BH(4)) treatment on brain function in individuals with phenylketonuria()

Phenylketonuria (PKU) is a rare genetic condition characterized by an absence or mutation of the PAH enzyme, which is necessary for the metabolism of the amino acid phenylalanine into tyrosine. Recently, sapropterin dihydrochloride, a synthetic form of tetrahydrobiopterin (BH(4)), has been introduce...

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Autors principals: Christ, Shawn E., Moffitt, Amanda J., Peck, Dawn, White, Desirée A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871382/
https://ncbi.nlm.nih.gov/pubmed/24371792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2013.08.012
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