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Molecules in mammalian brain that interact with the colchicine site on tubulin.

Colchicine, a plant alkaloid, is a potent inhibitor of mitosis and other physiological processes that involve microtubules. These effects are mediated by the specific binding of colchicine to a high-affinity receptor site on tubulin, the major protein of microtubules. It seemed possible that the col...

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Detalles Bibliográficos
Autor Principal: Lockwood, A H
Formato: Artigo
Idioma:Inglês
Publicado: 1979
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC383214/
https://ncbi.nlm.nih.gov/pubmed/286303
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