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Modular Assembly of Dimeric HIV Fusion Inhibitor Peptides with Enhanced Antiviral Potency

The HIV-1 envelope gp120/gp41 glycoprotein complex plays a critical role in virus-host cell membrane fusion and has been a focus for the development of HIV fusion inhibitors. In this paper, we present the synthesis of dimers of HIV fusion inhibitor peptides C37H6 and CP32M, which target the trimeric...

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Detalhes bibliográficos
Main Authors: Xiao, Junpeng, Tolbert, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832134/
https://ncbi.nlm.nih.gov/pubmed/24094817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.09.034
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