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Simplified method for determination of clarithromycin in human plasma using protein precipitation in a 96-well format and liquid chromatography-tandem mass spectrometry

A simplified method to determine clarithromycin concentrations in human plasma using protein precipitation in a 96-well plate and liquid chromatography tandem mass spectrometry was developed and validated. Plasma proteins were precipitated with acetonitrile and roxithromycin was used as the internal...

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Bibliografiske detaljer
Main Authors: Shin, Jaekyu, Pauly, Daniel F., Johnson, Julie A., Frye, Reginald F.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832059/
https://ncbi.nlm.nih.gov/pubmed/18639501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2008.06.050
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