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Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates

A rapid method to determine fexofenadine concentrations in human plasma using protein precipitation in 96-well plates and liquid chromatography-tandem mass spectrometry was validated. Plasma proteins were precipitated with acetonitrile containing the internal standard fexofenadine-d6, mixed briefly,...

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Detalhes bibliográficos
Main Authors: Stanton, Melonie L., Joy, Melanie S., Frye, Reginald F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818817/
https://ncbi.nlm.nih.gov/pubmed/20045385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2009.12.022
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