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Symmetric GroEL:GroES(2) complexes are the protein-folding functional form of the chaperonin nanomachine
Using calibrated FRET, we show that the simultaneous occupancy of both rings of GroEL by ATP and GroES occurs, leading to the rapid formation of symmetric GroEL:GroES(2) “football” particles regardless of the presence or absence of substrate protein (SP). In the absence of SP, these symmetric partic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832010/ https://ncbi.nlm.nih.gov/pubmed/24167279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318862110 |
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