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Intracellular domain of brain endothelial ICAM-1 is essential for T-lymphocyte-mediated signalling and migration

In order to examine the role of the ICAM-1 C-terminal domain in mediating transendothelial T-lymphocyte migration and ICAM-1 mediated signal transduction. Mutant human ICAM-1 molecules were expressed in rat brain microvascular endothelial cells. Expression of human wild type ICAM-1 in rat brain endo...

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Autori principali: Greenwood, John, Amos, Claire L., Walters, Claire E., Couraud, Pierre-Olivier, Lyck, Ruth, Engelhardt, Britta, Adamson, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831576/
https://ncbi.nlm.nih.gov/pubmed/12902516
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