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Comparison of immortalized bEnd5 and primary mouse brain microvascular endothelial cells as in vitro blood–brain barrier models for the study of T cell extravasation

Important insights into the molecular mechanism of T cell extravasation across the blood–brain barrier (BBB) have already been obtained using immortalized mouse brain endothelioma cell lines (bEnd). However, compared with bEnd, primary brain endothelial cells have been shown to establish better barr...

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Detalhes bibliográficos
Main Authors: Steiner, Oliver, Coisne, Caroline, Engelhardt, Britta, Lyck, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049495/
https://ncbi.nlm.nih.gov/pubmed/20606687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.96
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