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The topology of the yeast Ras converting enzyme as inferred from cysteine accessibility studies

The Ras converting enzyme (Rce1p) is an endoprotease that is involved in the post-translational processing of the Ras GTPases and other isoprenylated proteins. Its role in Ras biosynthesis marks Rce1p as an anti-cancer target. By assessing the chemical accessibility of cysteine residues substituted...

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Detalhes bibliográficos
Main Authors: Hildebrandt, Emily R., Davis, Dillon M., Deaton, John, Krishnankutty, Ranjith K., Lilla, Edward, Schmidt, Walter K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831529/
https://ncbi.nlm.nih.gov/pubmed/23972033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400647c
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