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Mutational Analysis of the Ras Converting Enzyme Reveals a Requirement for Glutamate and Histidine Residues

The Ras converting enzyme (RCE) promotes a proteolytic activity that is required for the maturation of Ras, the yeast a-factor mating pheromone, and certain other proteins whose precursors bear a C-terminal CAAX tetrapeptide motif. Despite the physiological importance of RCE, the enzymatic mechanism...

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Detalhes bibliográficos
Main Authors: Plummer, Lisa J., Hildebrandt, Emily R., Porter, Stephen B., Rogers, Victoria A., McCracken, Jay, Schmidt, Walter K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937830/
https://ncbi.nlm.nih.gov/pubmed/16361710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M506284200
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