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Prediction and experimental validation of enzyme substrate specificity in protein structures
Structural Genomics aims to elucidate protein structures to identify their functions. Unfortunately, the variation of just a few residues can be enough to alter activity or binding specificity and limit the functional resolution of annotations based on sequence and structure; in enzymes, substrates...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831482/ https://ncbi.nlm.nih.gov/pubmed/24145433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305162110 |
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